IDRA-21 Powder

IDRA-21 Powder

Chemical Name: 7-Chloro-3-(3-methyl-2-oxobutyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide
Synonyms: IDRA21; IDRA-21; Benzothiadiazine derivative
CAS Number: 22503-72-6
Molecular Formula: C₁₂H₁₃ClN₂O₄S
Molecular Weight: 316.76 g/mol
Form: Fine crystalline powder
Solubility: Soluble in ethanol and DMSO; low solubility in water
Appearance: White to off-white powder
Storage Conditions: Store in a cool, dry environment away from light and moisture. Reseal container tightly after each use.

IDRA-21 is a synthetic benzothiadiazine derivative that has been investigated in various laboratory settings for its positive allosteric modulation of AMPA receptors. Research has focused on its potential to enhance glutamatergic signaling, influence synaptic plasticity, and modulate cognitive pathways through non-NMDA receptor mechanisms. Its structural and pharmacological properties have made it a compound of interest in studies exploring AMPAkine-like activity and related neurophysiological processes.